{"title":"Adenovirus (Register and log in to see discounts)","description":"\u003ch3\u003e\u003cspan style=\"color: #ff2a00;\"\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp\u003eAdenoviral vectors are a versatile research tool with a number of positive aspects. The recombinant viruses can infect dividing and non-dividing cells, support transient, high-level protein expression, and are also easily amplified and purified to high concentrations (1x10\u003csup\u003e10\u003c\/sup\u003e\u003cspan\u003epfu\/mL-1x10\u003c\/span\u003e\u003csup\u003e11\u003c\/sup\u003e\u003cspan\u003epfu\/mL). They can accommodate inserts of up to 8 kb under normal circumstances. Larger inserts are possible, provided that an equivalent part of the viral genome has been properly deleted. The Viral Vector Core (VVC) is equipped to produce adenoviral vectors with inserts up to 10kb.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eThe University of Iowa VVC developed and currently uses the RAPAd\u003csup\u003eTM\u003c\/sup\u003e system (U.S. Patent No. 6,830,920 B2). A description of the system can be found in \"A simple method for the rapid generation of recombinant adenovirus vectors\" published in \u003ca href=\"http:\/\/www.nature.com\/cgi-taf\/DynaPage.taf?file=\/gt\/journal\/v7\/n12\/abs\/3301197a.html\u0026amp;dynoptions=doi1055343615\" title=\"1034-1038, 2000\" target=\"_blank\"\u003eGene Therapy 7:1034-1038, 2000\u003c\/a\u003e. This system eliminates many of the challenges of standard adenoviral production. The RAPAd\u003csup\u003eTM\u003c\/sup\u003e construction plasmids have left-hand ITR, E1a, and partial E1b sequence deletions which greatly reduces wild type occurrence in the final vector preparations. There is, therefore, no need for time-consuming plaque purification steps. All virus preps are tested for replication competent adenovirus (RCA) contamination by immuno-staining procedures.\u003c\/p\u003e\n\u003cp\u003eThe RAPAd\u003csup\u003eTM\u003c\/sup\u003e system uses a two plasmid transfection system for initial viral rescue, the viral shuttle plasmid and the viral backbone plasmid. The viral shuttle plasmid contains the gene of interest that the recombinant virus will produce, as well as a few viral protein sequences. The viral backbone contains the remaining viral proteins as well as a region of homology to the viral shuttle plasmid. After linearization and transfection into HEK293 cells (which provide the needed E1 and E3 proteins), the plasmids undergo homologous recombination to produce a full length adenoviral genome with the gene of interest inserted into the E1 region. The VVC has a number of backbones with additional E3 deletions that have reporter genes (i.e. eGFP, Beta-gal, mCherry, etc) inserted into them or that can be used for inserts larger than 8kb. Using viral backbones with reporters already inserted into the E3 region allows for reporter gene function without any additional cloning. This system also offers the possibility of expressing two separate proteins with custom made backbones. For more information contact \u003ca href=\"mailto:vectors@uiowa.edu\"\u003evectors@uiowa.edu\u003c\/a\u003e. \u003c\/p\u003e","products":[{"product_id":"ad5cmvcre-egfp","title":"Ad5CMVCre-eGFP","description":"\u003cp\u003eAd5CMVCre-eGFP (Standard Titer): Adenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of the Cre Recombinase protein fused to the enhanced green fluorescent protein (EGFP). Titer range 1x10^10 to 7x10^10 pfu\/ml.\u003c\/p\u003e\n\u003cp\u003eBiosafety Information for Ad5CMVCre-eGFP:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-4%20Ad5CMVeGFP%20BioSafety%20Information.pdf\" data-mce-selected=\"inline-boundary\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-4%20Ad5CMVeGFP%20BioSafety%20Information.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576501648,"sku":"VVC-U of Iowa-1174","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":40576501712,"sku":"VVC-U of Iowa-1174-100ul","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvcre-egfp-high-titer","title":"Ad5CMVCre-eGFP (High Titer)","description":"\u003cp\u003eAd5CMVCre-eGFP (High Titer): Adenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of the Cre Recombinase protein fused to the enhanced green fluorescent protein (EGFP). Titer range 8x10^10 to 2x10^11 pfu\/ml.\u003c\/p\u003e\n\u003cp\u003eBiosafety Information for Ad5CMVCre-eGFP:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-1174%20Ad5CMVCre-eGFP%20Biosafety%20Information.pdf\" data-mce-selected=\"inline-boundary\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-1174%20Ad5CMVCre-eGFP%20Biosafety%20Information.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576501776,"sku":"VVC-U of Iowa-1174-HT","price":4758.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":40576501840,"sku":"VVC-U of Iowa-1174-HT100ul","price":611.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvegfp","title":"Ad5CMVeGFP","description":"\u003cp\u003eAd5CMVeGFP (Standard Titer): Adenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of enhanced green fluorescent protein (EGFP).Titer range 1x10^10 to 5x10^10 pfu\/ml.\u003c\/p\u003e\n\u003cp\u003eBiosafety information for Ad5CMVeGFP:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2024-04\/U%20of%20Iowa-4%20Ad5CMVeGFP%20BioSafety%20Information.pdf\" data-mce-selected=\"inline-boundary\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2024-04\/U%20of%20Iowa-4%20Ad5CMVeGFP%20BioSafety%20Information.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576501904,"sku":"VVC-U of Iowa-4","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":40576501968,"sku":"VVC-U of Iowa-4-100ul","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvegfp-high-titer","title":"Ad5CMVeGFP (High Titer)","description":"\u003cp\u003eAd5CMVeGFP (High Titer): Adenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of enhanced green fluorescent protein (EGFP). Titer range 8x10^10 to 2x10^11 pfu\/ml.\u003c\/p\u003e\n\u003cp\u003eBiosafety information for Ad5CMVeGFP:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2024-04\/U%20of%20Iowa-4%20Ad5CMVeGFP%20BioSafety%20Information.pdf\" data-mce-selected=\"inline-boundary\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2024-04\/U%20of%20Iowa-4%20Ad5CMVeGFP%20BioSafety%20Information.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul (High Titer)","offer_id":12602026524757,"sku":"VVC-U of Iowa-4-HT","price":4758.0,"currency_code":"USD","in_stock":true},{"title":"100ul (High Titer)","offer_id":12602083115093,"sku":"VVC-U of Iowa-4-HT","price":611.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvcre","title":"Ad5CMVCre","description":"\u003cp\u003eAd5CMVCre (Standard Titer): Adenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of the Cre Recombinase protein. Titer range 1x10^10 to 7x10^10 pfu\/ml.\u003c\/p\u003e\n\u003cp\u003eBiosafety information for Ad5CMVCre:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-5%20Ad5CMVCre%20Biosafety%20Information.pdf\" title=\"Ad5CMVCre BioSafety information\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-5%20Ad5CMVCre%20Biosafety%20Information.pdf\u003c\/a\u003e \u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576502096,"sku":"VVC-U of Iowa-5","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":40576502160,"sku":"VVC-U of Iowa-5-100ul","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvcre-high-titer","title":"Ad5CMVCre (High Titer)","description":"\u003cp\u003eAd5CMVCre (High Titer): Adenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of the Cre Recombinase protein. Titer range 8x10^10 to 2x10^11 pfu\/ml. Please see Ad5CMVCre (Max High Titer) if your experiments need extreme or assured high titer particle density. \u003c\/p\u003e\n\u003cp\u003eBiosafety information for Ad5CMVCre:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-5%20Ad5CMVCre%20Biosafety%20Information.pdf\" data-mce-selected=\"inline-boundary\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-5%20Ad5CMVCre%20Biosafety%20Information.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576502224,"sku":"VVC-U of Iowa-5-HT","price":4758.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":40576502288,"sku":"VVC-U of Iowa-5-HT100ul","price":611.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvempty","title":"Ad5CMVempty","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter that expresses no protein and can be used as an empty control for many of our adenoviral vectors.\u003c\/p\u003e\n\u003cp\u003eBiosafety information for Ad5CMVempty:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-272%20Ad5CMVempty%20BioSafety%20Information.pdf\" data-mce-selected=\"inline-boundary\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-272%20Ad5CMVempty%20BioSafety%20Information.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"100ul","offer_id":40576502352,"sku":"VVC-U of Iowa-272-100ul","price":212.0,"currency_code":"USD","in_stock":true},{"title":"1000ul","offer_id":40576502416,"sku":"VVC-U of Iowa-272","price":1338.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvmcherry","title":"Ad5CMVmCherry","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the mCherry fluorescent protein.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576502544,"sku":"VVC-U of Iowa-537","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":12575681806421,"sku":"VVC-U of Iowa-537","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvntlacz","title":"Ad5CMVntLacZ","description":"\u003cp\u003eThis adenoviral vector expresses the _-galactosidase (LacZ) protein with a nuclear targeting signal under control of the CMV promoter. The addition of the nuclear targeting signal means that X-gal staining will only be present in the nucleus of infected cells\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576502608,"sku":"VVC-U of Iowa-1917","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":40576502672,"sku":"VVC-U of Iowa-1917-100ul","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvflpo","title":"Ad5CMVFlpo","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of Flpo recombinase protein, published from the lab of Dr. Philippe Soriano. A material transfer agreement is required for use of Flpo from Fred Hutchinson. Please email MTA@fredhutch.org to initiate this process. Once an MTA has been secured, please send a copy to vectors@uiowa.edu.\u003c\/p\u003e\n\u003cp\u003eBiosafety information for Ad5CMVFLPO:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-530%20Ad5CMVFLPO%20Biosafety%20Information.pdf\" data-mce-selected=\"inline-boundary\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-530%20Ad5CMVFLPO%20Biosafety%20Information.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576502928,"sku":"VVC-U of Iowa-530","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":40576502992,"sku":"VVC-U of Iowa-530-100ul","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvcytolacz","title":"Ad5CMVcytoLacZ","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of _-galactosidase (LacZ) protein. X-gal staining will be present throughout infected cells.\u003c\/p\u003e\n\u003cp\u003eBiosafety information:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-3554%20Ad5CMVCytoLacZ%20Biosafety%20Information.pdf\" data-mce-selected=\"inline-boundary\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-3554%20Ad5CMVCytoLacZ%20Biosafety%20Information.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576503056,"sku":"VVC-U of Iowa-3554","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":39436105220181,"sku":"VVC-U of Iowa-3554-100ul","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5mu6shsafe-rsvegfp","title":"Ad5mU6shSafe\/RSVeGFP","description":"\u003cp\u003eAdenoviral vector with Mouse U6 Promoter driving a scrambled shRNA control shSafe cassette followed by a second reporter cassette containing the RSV (Rous sarcoma virus) Promoter driving EGFP. Please reference: Boudreau, R. L., et al. (2011). \"Rational Design of Therapeutic siRNAs: Minimizing Off-targeting Potential to Improve the Safety of RNAi Therapy for Huntington's Disease.\" Mol Ther 19(12): 2169-2177.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576503120,"sku":"VVC-U of Iowa-2891","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":40576503184,"sku":"VVC-U of Iowa-2891-100ul","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5mu6shsafe-rsvmcherry","title":"Ad5mU6shSafe\/RSVmCherry","description":"\u003cp\u003eAdenoviral vector with Mouse U6 Promoter driving a scrambled shRNA control shSafe cassette followed by a second reporter cassette containing the RSV (Rous sarcoma virus) Promoter driving mCherry fluorescent protein. Please reference: Boudreau, R. L., et al. (2011). \"Rational Design of Therapeutic siRNAs: Minimizing Off-targeting Potential to Improve the Safety of RNAi Therapy for Huntington's Disease.\" Mol Ther 19(12): 2169-2177.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576503248,"sku":"VVC-U of Iowa-3086","price":1338.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5mu6misafe-rsvmcherry","title":"Ad5mU6miSafe\/RSVmCherry","description":"\u003cp\u003eAdenoviral vector with Mouse U6 Promoter driving a scrambled miRNA control miSafe cassette followed by a second reporter cassette containing the RSV (Rous sarcoma virus) Promoter driving mCherry fluorescent protein.Please reference: Boudreau, R. L., et al. (2011). \"Rational Design of Therapeutic siRNAs: Minimizing Off-targeting Potential to Improve the Safety of RNAi Therapy for Huntington's Disease.\" Mol Ther 19(12): 2169-2177.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576503760,"sku":"VVC-U of Iowa-3085","price":1338.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5mu6misafe-rsvegfp","title":"Ad5mU6miSafe\/RSVeGFP","description":"\u003cp\u003eAdenoviral vector with Mouse U6 Promoter driving a scrambled miRNA control miSafe cassette followed by a second reporter cassette containing the RSV (Rous sarcoma virus) Promoter driving EGFP.Please reference: Boudreau, R. L., et al. (2011). \"Rational Design of Therapeutic siRNAs: Minimizing Off-targeting Potential to Improve the Safety of RNAi Therapy for Huntington's Disease.\" Mol Ther 19(12): 2169-2177.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576504336,"sku":"VVC-U of Iowa-2893","price":1338.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvntegfp","title":"Ad5CMVnteGFP","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of nuclear targeted enhanced green fluorescent protein (EGFP). This vector is a good control for the Ad5CMVCre-EGFP as the Cre targets the fused eGFP to the nucleus.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576504848,"sku":"VVC-U of Iowa-2449","price":1338.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5mspc-cre","title":"Ad5mSPC-Cre","description":"\u003cp\u003eAdenoviral vector with Surfactant Protein C Promoter driving the expression of Cre Recombinase. \u003cspan\u003ePlease acknowledge Dr. Anton Berns from the Netherlands Cancer Institute in any publications using this virus (a.berns2@nki.nl).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eBiosafety information:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/Berns-1168%20Ad5mSPC-Cre%20Biosafety%20Information.pdf\" data-mce-selected=\"inline-boundary\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/Berns-1168%20Ad5mSPC-Cre%20Biosafety%20Information.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576505104,"sku":"VVC-Berns-1168","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":12483454533717,"sku":"VVC-Berns-1168","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cgrp-cre","title":"Ad5CGRP-Cre","description":"\u003cp\u003eAdenoviral vector with Calcitonin Gene-related Peptide Promoter driving the expression of Cre Recombinase. Please acknowledge Dr. Anton Berns from the Netherlands Cancer Institute in any publications using this virus (a.berns2@nki.nl).\u003c\/p\u003e\n\u003cp\u003eBiosafety information:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/Berns-1160%20Ad5CGRPCre%20Biosafety%20Information_0.pdf\" data-mce-selected=\"inline-boundary\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/Berns-1160%20Ad5CGRPCre%20Biosafety%20Information_0.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576505168,"sku":"VVC-Berns-1160","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":40576505232,"sku":"VVC-Berns-1160-100ul","price":212.0,"currency_code":"USD","in_stock":true},{"title":"1ml in 25ul aliquots","offer_id":50553903350063,"sku":"VVC-Berns-1160-1ml in 25ul","price":2180.0,"currency_code":"USD","in_stock":true},{"title":"25ul Tester. Special Request. Contact vectors@uiowa.edu","offer_id":50553906004271,"sku":"VVC-Berns-1160-25ul-tester","price":25.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cc10-cre","title":"Ad5CC10-Cre","description":"\u003cp\u003eAdenoviral vector with lung-specific CC10 Promoter driving the expression of Cre Recombinase. Please acknowledge Dr. Anton Berns from the Netherlands Cancer Institute in any publications using this virus (a.berns2@nki.nl).\u003c\/p\u003e\n\u003cp\u003eBiosafety information:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/Berns-1166%20Ad5CC10-Cre%20Biosafety%20Information.pdf\" data-mce-selected=\"inline-boundary\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/Berns-1166%20Ad5CC10-Cre%20Biosafety%20Information.pdf\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576505296,"sku":"VVC-Berns-1166","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":12483381952597,"sku":"VVC-Berns-1166","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5-bk5-cre","title":"Ad5-bk5-Cre","description":"\u003cp\u003eAdenoviral vector with Bovine Keratin 5 Promoter driving the expression of Cre Recombinase. Please acknowledge Dr. Anton Berns from the Netherlands Cancer Institute in any publications using this virus (a.berns2@nki.nl). Regular titer range 1E+10 pfu\/ml to 7E+10 pfu\/ml. \u003c\/p\u003e\n\u003cp\u003eBiosafety information:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/Berns-1547%20Ad5-bK5-Cre%20Biosafety%20Information.pdf\" data-mce-selected=\"inline-boundary\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/Berns-1547%20Ad5-bK5-Cre%20Biosafety%20Information.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576505360,"sku":"VVC-Berns-1547","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":39399016005717,"sku":"VVC-Berns-1547","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvcre-mcherry","title":"Ad5CMVCre-mCherry","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of Cre recombinase fused to the mCherry florescent protein.\u003c\/p\u003e\n\u003cp\u003eBiosafety information for Ad5CMVCre-mCherry:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-537%20Ad5CMVmCherry%20Biosafety%20Information.pdf\" data-mce-selected=\"inline-boundary\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-537%20Ad5CMVmCherry%20Biosafety%20Information.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576505424,"sku":"VVC-U of Iowa-649","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":664534253584,"sku":"VVC-U of Iowa-649-100ul","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvgpx-1","title":"Ad5CMVGpx-1","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of glutathione peroxidase-1. The vector was generated by the laboratory of Dr. John Engelhardt, referenced below. Please e-mail vectors@uiowa.edu for permission to acquire this virus. Please Reference: Li, Q., S. Sanlioglu, et al. (2001). \"GPx-1 gene delivery modulates NFkappaB activation following diverse environmental injuries through a specific subunit of the IKK complex.\" Antioxid Redox Signal 3(3): 415-32.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576505552,"sku":"VVC-Engelhardt-1337","price":1338.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvcatalase","title":"Ad5CMVCatalase","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of Catalase. The vector was generated by the laboratory of Dr. John Engelhardt, referenced below. Please e-mail vectors@uiowa.edu for permission to acquire this virus. Please Reference: Lam, E. W., R. Zwacka, et al. (1999). \"Effects of antioxidant enzyme overexpression on the invasive phenotype of hamster cheek pouch carcinoma cells.\" Free Radic Biol Med 27(5-6): 572-9.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576505616,"sku":"VVC-Engelhardt-3950","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":50246589350191,"sku":"VVC-Engelhardt-3950-100ul","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvsod1cu-zn","title":"Ad5CMVSOD1(Cu\/Zn)","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of Copper-Zinc-containing Superoxide Dismutase. The vector was generated by the laboratory of Dr. John Engelhardt, referenced below. Please e-mail vectors@uiowa.edu for permission to acquire this virus. Please Reference: Zwacka, R. M., L. Dudus, et al. (1998). \"Redox gene therapy protects human IB-3 lung epithelial cells against ionizing radiation-induced apoptosis.\" Hum Gene Ther 9(9): 1381-6.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576505680,"sku":"VVC-Engelhardt-3951","price":1338.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvsod2mn","title":"Ad5CMVSOD2(Mn)","description":"\u003cp\u003e_Adenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of Manganese-containing Superoxide Dismutase. The vector was generated by the laboratory of Dr. John Engelhardt, referenced below. Please e-mail vectors@uiowa.edu for permission to acquire this virus. Please Reference: Zwacka, R. M., W. Zhou, et al. (1998). \"Redox gene therapy for ischemia\/reperfusion injury of the liver reduces AP1 and NF-kappaB activation.\" Nat Med 4(6): 698-704.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576505744,"sku":"VVC-Engelhardt-3952","price":1338.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvikkbetak-a","title":"Ad5CMVIKKbeta(K\/A)","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of IKKbeta(dominant negative mutant K44A). The vector was generated by the laboratory of Dr. John Engelhardt, referenced below. Please e-mail vectors@uiowa.edu for permission to acquire this virus. Please Reference: Sanlioglu, S., C. M. Williams, et al. (2001). \"Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-alpha secretion through IKK regulation of NF-kappa B.\" J Biol Chem 276(32): 30188-98.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576505872,"sku":"VVC-Engelhardt-3953","price":1338.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvikkbetak-m","title":"Ad5CMVIKKbeta(K\/M)","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of IKKbeta(dominant negative mutant K44M). The vector was generated by the laboratory of Dr. John Engelhardt, referenced below. Please e-mail vectors@uiowa.edu for permission to acquire this virus. Please Reference: Sanlioglu, S., C. M. Williams, et al. (2001). \"Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-alpha secretion through IKK regulation of NF-kappa B.\" J Biol Chem 276(32): 30188-98.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576505936,"sku":"VVC-Engelhardt-3954","price":1338.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvikappabalphay42f","title":"Ad5CMVIkappaBalpha(Y42F)","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of IkappaBalpha(mutant Y42F). The vector was generated by the laboratory of Dr. John Engelhardt, referenced below. Please e-mail vectors@uiowa.edu for permission to acquire this virus. Please Reference: Fan, C., Li, Q., Zhang, Y., Liu, X., Luo, M., Abbott, D., Zhou, W., and Engelhardt, J.F. 2004. IkappaBalpha and IkappaBbeta possess injury context-specific functions that uniquely influence hepatic NF-kappaB induction and inflammation. J Clin Invest 113:746-755.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576506256,"sku":"VVC-Engelhardt-3955","price":1338.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvikappabalphaantisense","title":"Ad5CMVIkappaBalpha(AntiSense)","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of antisense IkappaBalpha mRNA. The vector was generated by the laboratory of Dr. John Engelhardt, referenced below. Please e-mail vectors@uiowa.edu for permission to acquire this virus. Please Reference: Fan, C., Yang, J., and Engelhardt, J.F. 2002. Temporal Pattern of NFkappaB Activation Influences Apoptotic Cell Fate in a Stimuli Dependent Fashion. Journal of Cell Science 115, 4843-4853.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576506832,"sku":"VVC-Engelhardt-3959","price":1338.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5nfkb-luciferase","title":"Ad5NFkB-Luciferase","description":"\u003cp\u003eAdenoviral vector with four tandem copies of the NF_B consensus sequence fused to a TATA-like promoter from the herpes simplex virus-thymidine kinase gene acts as a promoter to drive expression of Luciferase. The vector was generated by the laboratory of Dr. John Engelhardt, referenced below.  Please Reference: Sanlioglu, S., C. M. Williams, et al. (2001). \"Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-alpha secretion through IKK regulation of NF-kappa B.\" J Biol Chem 276(32): 30188-98.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576507408,"sku":"VVC-Engelhardt-3956","price":1338.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvn17rac1-ha","title":"Ad5CMVN17Rac1-HA","description":"\u003cp\u003e_Adenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of dominant-negative Rac1 containing a substitution at position 17. Rac1 is also tagged with an N-terminal HA.The vector was generated by the laboratory of Dr. John Engelhardt, referenced below. Please e-mail vectors@uiowa.edu for permission to acquire this virus. Please Reference: Zimmerman, Dunlay, Lazartigues, Zhang, Sharma, Engelhardt, Davisson. Requirement for Rac1-dependent NADPH oxidase in the cardiovascular and dipsogenic actions of AngII in the Brain. Circ. Res. 2004;95:532-539.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576507984,"sku":"VVC-Engelhardt-3957","price":1338.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvwtrac1-ha","title":"Ad5CMVwtRac1-HA","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of wild-type Rac1, which also has an N-terminal HA tag.The vector was generated by the laboratory of Dr. John Engelhardt, referenced below. Please e-mail vectors@uiowa.edu for permission to acquire this virus. Please Reference: Zimmerman, Dunlay, Lazartigues, Zhang, Sharma, Engelhardt, Davisson. Requirement for Rac1-dependent NADPH oxidase in the cardiovascular and dipsogenic actions of AngII in the Brain. Circ. Res. 2004;95:532-539.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576508560,"sku":"VVC-Engelhardt-3958","price":1338.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvhdpp4-myc-flag","title":"Ad5CMVhDPP4-myc-flag","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of wild-type human DPP4, which also has C-terminal myc and flag tags.The vector was generated by the laboratories of Stanley Perlman, MD, PhD and Paul McCray, MD. \u003cbr\u003ePlease reference: Zhao J, Li K, Wohlford-Lenane C, Agnihothram S, Fett C, Zhao J, Gale M, Baric R, Enjuanes L, Gallagher T, McCray P, Perlman S. Rapid generation of a mouse model for Middle East respiratory syndrome. Proc Natl Acad Sci U S A. 2014 April 1. 111(13):4970-5.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":40576509008,"sku":"VVC-Perlman-1615","price":1338.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvcas9","title":"Ad5CMVspCas9","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter that expresses the CRISPR* human spCas9 nuclease. \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e*10% royalty fee has been added to the pricing of this vector to be sent to the Broad Institute for CRISPR technology. \u003c\/span\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"100ul","offer_id":40576510096,"sku":"VVC-U of Iowa-4683-100ul","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvflpo-high-titer","title":"Ad5CMVFlpo (High Titer)","description":"\u003cp\u003e\u003cspan\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of Flpo recombinase protein, published from the lab of Dr. Philippe Soriano. A material transfer agreement is required for use of Flpo from Fred Hutchinson. Please email MTA@fredhutch.org to initiate this process. Once an MTA has been secured, please send a copy to vectors@uiowa.edu.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eBiosafety information for Ad5CMVFLPO:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-530%20Ad5CMVFLPO%20Biosafety%20Information.pdf\" data-mce-selected=\"inline-boundary\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-530%20Ad5CMVFLPO%20Biosafety%20Information.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":272277405712,"sku":"VVC-U of Iowa-530HT","price":4758.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":272277438480,"sku":"VVC-U of Iowa-530HT-100ul","price":611.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvcre-mcherry-high-titer","title":"Ad5CMVCre-mCherry (High Titer)","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of Cre recombinase fused to the mCherry florescent protein.\u003c\/p\u003e\n\u003cp\u003eBiosafety information for Ad5CMVCre-mCherry:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-537%20Ad5CMVmCherry%20Biosafety%20Information.pdf\" data-mce-selected=\"inline-boundary\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-537%20Ad5CMVmCherry%20Biosafety%20Information.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":343970054160,"sku":"VVC-U of Iowa-649HT","price":4758.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvcre-1ml-in-25ul-aliquots","title":"Ad5CMVCre (1ml in 25ul aliquots)","description":"\u003cp\u003eAd5CMVCre (Standard Titer): Adenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of the Cre Recombinase protein. Titer range 1x10^10 to 7x10^10 pfu\/ml. 1ml in 25ul. Not sold as individual 25ul aliquots. Not an in stock vector. Please allow 4-6 weeks for production and delivery. \u003c\/p\u003e\n\u003cp\u003eBiosafety information for Ad5CMVCre:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-5%20Ad5CMVCre%20Biosafety%20Information.pdf\" data-mce-selected=\"inline-boundary\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-5%20Ad5CMVCre%20Biosafety%20Information.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":387500736528,"sku":"VVC-U of Iowa-5-sa","price":2180.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvempty-ht-1000ul","title":"Ad5CMVempty (High Titer)","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter that expresses no protein and can be used as an empty control for many of our adenoviral vectors. High titer. Titer range 8x10^10 to 2x10^11 pfu\/ml. \u003c\/p\u003e\n\u003cp\u003eBiosafety information for Ad5CMVempty:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/medicine.uiowa.edu\/vectorcore\/sites\/medicine.uiowa.edu.vectorcore\/files\/U%20of%20Iowa-272%20Ad5CMVempty%20Biosafety%20Information.pdf\" title=\"Ad5CMVempty Biosafety information\"\u003ehttps:\/\/medicine.uiowa.edu\/vectorcore\/sites\/medicine.uiowa.edu.vectorcore\/files\/U%20of%20Iowa-272%20Ad5CMVempty%20Biosafety%20Information.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"100ul","offer_id":12218886127701,"sku":"VVC-U of Iowa-272-HT100ul","price":611.0,"currency_code":"USD","in_stock":true},{"title":"1000ul","offer_id":12218886160469,"sku":"VVC-U of Iowa-272-HT","price":4758.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvcas9-rsvegfp","title":"Ad5CMVspCas9\/RSVeGFP","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter that expresses the CRISPR* human spCas9 nuclease.RSV (Rous sarcoma virus) promoter separately drives expression of eGFP (enhanced green fluorescent protein).\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e*10% royalty fee has been added to the pricing of this vector to be sent to the Broad Institute for CRISPR technology. \u003c\/span\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"100ul","offer_id":21186692087893,"sku":"VVC-U of Iowa-6935","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvcre-max-high-titer","title":"Ad5CMVCre (Max High Titer)","description":"\u003cp\u003eAd5CMVCre (Max High Titer): Adenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of the Cre Recombinase protein. Assured titer range 2x10^11 to 3x10^11 pfu\/ml. 2ml in 25ul aliquots or individual 100ul aliquots. 25ul Tester aliquots can be ordered prior to purchase of full 2ml in 25ul. \u003c\/p\u003e\n\u003cp\u003eSometimes in stock but usually by special order. Please allow 8-12 weeks. Please contact vectors@uiowa.edu for additional information.  \u003c\/p\u003e\n\u003cp\u003eBiosafety information for Ad5CMVCre:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-5%20Ad5CMVCre%20Biosafety%20Information.pdf\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/U%20of%20Iowa-5%20Ad5CMVCre%20Biosafety%20Information.pdf\u003c\/a\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"2000ul in 25ul","offer_id":21232869474389,"sku":"VVC-U of Iowa-5-MHT-1000ul","price":12500.0,"currency_code":"USD","in_stock":true},{"title":"25ul Tester for purchase of  full 1ml x 25ul","offer_id":44203214111023,"sku":"VVC-U of Iowa-5MHT Tester","price":25.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5mspc-flpo","title":"Ad5mSPC-Flpo","description":"\u003cp\u003eAdenoviral vector with \u003cspan\u003eSurfactant Protein C \u003c\/span\u003epromoter driving the expression of Flpo recombinase protein, published from the lab of Dr. Philippe Soriano. A material transfer agreement is required for use of Flpo from Fred Hutchinson. Please email MTA@fredhutch.org to initiate this process. Once an MTA has been secured, please send a copy to vectors@uiowa.edu.\u003c\/p\u003e\n\u003cp\u003eThe mSPC promoter in this vector is specific to type II pneumocytes in the lung. Please acknowledge Dr. Eric Snyder from the Huntsman Cancer Institute in any publications using this virus. eric.snyder@hci.utah.edu.\u003c\/p\u003e\n\u003cp\u003eBiosafety information for Ad5mSPC-FLPO:\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/Snyder-6695%20Ad5mSPC-FLPO%20Biosafety%20Information.pdf\" data-mce-fragment=\"1\" data-mce-href=\"https:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/Snyder-6695%20Ad5mSPC-FLPO%20Biosafety%20Information.pdf\" data-mce-selected=\"inline-boundary\"\u003ehttps:\/\/vectorcore.medicine.uiowa.edu\/sites\/vectorcore.medicine.uiowa.edu\/files\/2023-11\/Snyder-6695%20Ad5mSPC-FLPO%20Biosafety%20Information.pdf\u003c\/a\u003e \u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":21258089300053,"sku":"VVC-Snyder-6695","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":21258089332821,"sku":"VVC-Snyder-6695","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvflexegfp","title":"Ad5CMVFLEXeGFP","description":"\u003cp\u003eAd5CMVFLEXeGFP (Standard Titer): Adenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of Cre-dependent double floxed enhanced green fluorescent protein (EGFP).Titer range 1x10^10 to 5x10^10 pfu\/ml.\u003c\/p\u003e\n\u003cp\u003eBiosafety information for Ad5CMVFLEXeGFP:\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":21969666474069,"sku":"VVC-U of Iowa-1697","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":21971128221781,"sku":"VVC-U of Iowa-1697-100ul","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvflexmcherry","title":"Ad5CMVFLEXmCherry","description":"\u003cp\u003eAd5CMVFLEXmCherry (Standard Titer): Adenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of Cre-dependent double floxed mCherry.Titer range 1x10^10 to 5x10^10 pfu\/ml.\u003c\/p\u003e\n\u003cp\u003eBiosafety information for Ad5CMVFLEXmCherry:\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":21969746722901,"sku":"VVC-U of Iowa-1693","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":21971173376085,"sku":"VVC-U of Iowa-1693-100ul","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5mk8-nlscre","title":"Ad5mK8-nlsCre","description":"\u003cp\u003eAd5mK8-nlsCre (Standard Titer): Adenoviral vector with mK8 (Keratin 8) promoter driving the expression of the Cre Recombinase protein. Titer range 1x10^10 to 5x10^10 pfu\/ml. Please acknowledge Dr. Zhe Li in any publications using this vector. \u003c\/p\u003e\n\u003cp\u003e\"Lineage Tracing of Mammary Epithelial Cells Using Cell-Type-Specific Cre-Expressing Adenoviruses\" published in Stem Cell Reports, 2014. Luwei Tao, Maaike P.A. van Bragt, Elizabeth Laudadio, and Zhe Li. \u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4050356\/\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4050356\/\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eBiosafety information for Ad5mK8-nlsCre:\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":22085536874581,"sku":"VVC-Li-535-1000ul","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":39482468139093,"sku":"VVC-Li-535-100ul","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cd14-cre","title":"Ad5mCD14-Cre","description":"\u003cp\u003eAd5CD14-Cre (Standard Titer): Adenoviral vector with mouse CD14 promoter driving the expression of the Cre Recombinase protein. Titer range 1x10^10 to 5x10^10 pfu\/ml.\u003c\/p\u003e\n\u003cp\u003eBiosafety information for Ad5mCD14-Cre COMING SOON.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":23072610484309,"sku":"VVC-U of Iowa-7308","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":23072610517077,"sku":"VVC-U of Iowa-7308-100ul","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvcre-wtiresmcherry","title":"Ad5CMVCre-wtIRESmCherry","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of Cre recombinase and mCherry florescent protein separated by a (IRES) internal ribosome entrance sequence.\u003c\/p\u003e\n\u003cp\u003eBiosafety information for Ad5CMVCre-wtIRESmCherry:\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":31544392974421,"sku":"VVC-U of Iowa-4307-1000ul","price":1211.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvnt-mcherry","title":"Ad5CMVnt-mCherry","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of nuclear targeted red fluorescent protein mCherry. This vector is a good control for the Ad5CMVCre-mCherry as the Cre targets the fused mCherry to the nucleus.\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":31545333612629,"sku":"VVC-U of Iowa-7501-1000ul","price":1338.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5mpcsk1cre","title":"Ad5mPcsk1Cre","description":"\u003cp\u003eAd5mPcsk1Cre (Standard Titer): Adenoviral vector with mPcsk1 (murine proprotein convertase subtilisin\/kexin type 1) promoter driving the expression of the Cre Recombinase protein. Titer range 1x10^10 to 5x10^10 pfu\/ml.\u003c\/p\u003e\n\u003cp\u003eBiosafety information:\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":31722749231189,"sku":"VVC-U of Iowa-7541","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":31722749263957,"sku":"VVC-U of Iowa-7541-100ul","price":212.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cc10-flpo","title":"Ad5CC10-Flpo","description":"\u003cp\u003eAdenoviral vector with \u003cspan\u003elung-specific CC10 Promoter driving the expression of\u003c\/span\u003e Flpo recombinase protein, published from the lab of Dr. Philippe Soriano. A material transfer agreement is required for use of Flpo from Fred Hutchinson. Please email MTA@fredhutch.org to initiate this process. Once an MTA has been secured, please send a copy to vectors@uiowa.edu. \u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":31769404309589,"sku":"VVC-U of Iowa-7553-1000ul","price":1338.0,"currency_code":"USD","in_stock":true}]},{"product_id":"ad5cmvace2","title":"Ad5CMVACE2-IRESeGFP","description":"\u003cp\u003eAdenoviral vector with CMV (Cytomegalovirus) promoter driving the expression of wild-type SARS receptor with weak eGFP expression from IRESeGFP. The vector was generated by the laboratories of Dr. Paul McCray and Dr. Stanley Perlman. \u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.pnas.org\/content\/111\/13\/4970.long\"\u003eRapid generation of a mouse model for Middle East\u003c\/a\u003e\u003cbr\u003e\u003ca href=\"https:\/\/www.pnas.org\/content\/111\/13\/4970.long\"\u003erespiratory syndrome\u003c\/a\u003e\u003c\/p\u003e","brand":"Iowa","offers":[{"title":"1000ul","offer_id":31851975311445,"sku":"VVC-McCray-7580","price":1338.0,"currency_code":"USD","in_stock":true},{"title":"100ul","offer_id":31944250884181,"sku":"VVC-McCray-7580-100","price":212.0,"currency_code":"USD","in_stock":true}]}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1994\/0085\/collections\/adenovirus.jpg?v=1497030336","url":"https:\/\/vectorcore-iowa.myshopify.com\/collections\/ad5.oembed?page=6","provider":"UI Viral Vector Core Web","version":"1.0","type":"link"}